Find Fast Relief and Lasting Hope Through Ketamine Therapy in Fort Lauderdale, FL

A Innovative Approach to Mental Health & Chronic Pain Treatment

Looking for ketamine for depression, anxiety, PTSD, or chronic pain management in South Florida? Visit One Mind Wellness and Ketamine in Fort Lauderdale.

What is Ketamine Therapy?

Ketamine offers a novel therapeutic option for treatment-resistant depression, anxiety, PTSD, addiction, and chronic pain conditions.

Initially created for anesthetic use, ketamine engages the brain’s glutamatergic pathways—a mechanism distinct from standard antidepressants.

 Delivered via controlled intravenous protocols under clinical supervision, it accelerates neural adaptation, enabling the formation of healthier synaptic connections.

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Ketamine for Mood Disorders

Ketamine treats mood disorders by blocking NMDA receptors in the brain, which triggers a cascade leading to increased glutamate release and production of brain-derived neurotrophic factor (BDNF). 

This promotes rapid growth of new synaptic connections in brain regions affected by depression, like the prefrontal cortex, potentially explaining why patients can experience relief from severe depression within hours rather than the weeks required for traditional antidepressants.

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Ketamine for Chronic Pain

Ketamine treats chronic pain by blocking NMDA receptors in the spinal cord and brain, which are involved in central sensitization—a process where the nervous system becomes hyperexcitable and amplifies pain signals. 

By interrupting this pathway, ketamine helps “reset” overactive pain circuits and reduce wind-up, where repeated signals become progressively amplified. This makes it particularly effective for neuropathic pain and complex regional pain syndrome, often providing relief when other medications fail.

The Ketamine Experience

the ketamine experience at one mind

Ketamine for Mental Health

When treating mood disorders, the ketamine experience is generally shorter but deeply impactful. 

The infusion itself lasts for 45 minutes, with your total time at the clinic ranging from 60 to 90 minutes. 

You will relax in a calm, private setting monitored by a medical professional. Many patients describe the sensation during the treatment as peaceful, floating, or emotionally releasing. 

Afterward, you might feel calm immediately, though some find their mood improves gradually over the next 24 to 72 hours.

Ketamine for Pain

For pain management, the ketamine experience is designed to be both comprehensive and comforting. 

Because the goal is sustained pain relief, the infusion itself lasts approximately 2 hours—longer than typical treatments for mood disorders. 

Including time for preparation and recovery, you should plan to be at the clinic for a total of 2.5 to 3 hours.

 Throughout your visit, you will rest in a calm, private setting under the direct care of a medical supervisor to ensure your safety and relaxation.

the ketamine experience at one mind

Transparent Healing

Real People, Real Results

Great people who care. I’m not a Dr, but I would recommend a loved one try this route prior to being prescribed to lifelong medications with a laundry list of side effects. Thank you again team.
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g m.
8/30/2026
Super staff! The treatment was stellar. One Mund was a light in a very dark place for me. I am forever grateful.
READ MORE
Jay S.
8/10/2026
Best money I’ve ever spent. Ketamine therapy helped quiet my racing thoughts and gave me a sense of peace I hadn’t felt in a long time. I’m sleeping better, getting out of bed with more energy, and I finally feel like I have my motivation back to focus on building my business. The entire team is incredibly kind, compassionate, and professional. They made me feel comfortable and, most importantly, safe throughout every session. I’m truly grateful for this experience and highly recommend this clinic to anyone looking for real support on their healing journey.
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Racquel J.
7/14/2026
I had an exceptional experience at One Mind Wellness and cannot recommend them highly enough. I was very nervous heading into my first session as I’m working through a lot of grief but from the moment I arrived I felt genuinely supported and cared for. Mike the concierge was incredibly kind and attentive and made sure I felt fully prepared and comfortable throughout the process. Dr. Topfer was extremely hands-on compassionate and thoughtful creating such a safe and reassuring environment. Even after my first session I noticed a sense of relief which has given me so much hope for the journey ahead. The entire team goes above and beyond to make the experience feel supportive professional and truly patient centered and I’m very grateful to have found them.
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Alexa D.
3/17/2026
I had an exceptional experience at One Mind Wellness, and I cannot recommend them highly enough.From the moment you walk in, you feel supported and cared for. Mike, the concierge, is wonderful — incredibly attentive, kind, and helpful throughout the entire process. He truly makes you feel comfortable and welcomed.Dr. Topfer and Dr. Greca are a top-notch team. Their professionalism, knowledge, and compassion made me feel that I was in the best possible hands. My neuropsychiatrist actually recommended ketamine therapy to me, which is what led me to One Mind Wellness, and I’m so grateful that I followed that advice.I completed six ketamine sessions, and the results have been life-changing. Before treatment, I struggled with rumination — my thoughts often felt stuck in a negative loop that I couldn’t break. Since completing the sessions, that pattern has lifted. I feel calmer, much less reactive, and more at peace mentally.I’ve also noticed improvements in my energy and my ability to focus. It truly feels like my mind has reset in a healthy way.My only regret is that I didn’t do this sooner.If you are considering ketamine therapy, you will be in excellent hands at One Mind Wellness.
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Kellie S.
3/08/2026
Dr. Graca and team are really top notch. I run a large healthcare company and know the industry well and these guys really go the extra mile. Ketamine saved me and I was so worried when moving from NYC, but Graca talked to all my other doctors and took great care of me
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Connor W.
12/24/2025
Great people who care. I’m not a Dr, but I would recommend a loved one try this route prior to being prescribed to lifelong medications with a laundry list of side effects. Thank you again team.
READ MORE
g m.
8/30/2026
Super staff! The treatment was stellar. One Mund was a light in a very dark place for me. I am forever grateful.
READ MORE
Jay S.
8/10/2026
Best money I’ve ever spent. Ketamine therapy helped quiet my racing thoughts and gave me a sense of peace I hadn’t felt in a long time. I’m sleeping better, getting out of bed with more energy, and I finally feel like I have my motivation back to focus on building my business. The entire team is incredibly kind, compassionate, and professional. They made me feel comfortable and, most importantly, safe throughout every session. I’m truly grateful for this experience and highly recommend this clinic to anyone looking for real support on their healing journey.
READ MORE
Racquel J.
7/14/2026

Why Choose One Mind for Your Ketamine Treatment?

We treat anxiety seriously. And we do it safely.

physician oversight
Physician-guided:

Every treatment is overseen by a board-certified anesthesiologist

tailored protocols
Tailored protocols

We adjust dosing to your unique needs

gold-standard
Gold-standard care

6 infusions over 2–3 weeks (research-backed protocol)

collaborative care
Collaborative model

We can coordinate with your therapist or psychiatrist

“Patients come in spinning out. They leave feeling like they can breathe again.”

integration support near me

Integration Support

We offer optional check-ins, guided reflections, or provider coordination after your infusions—so the breakthroughs you experience in-session carry into everyday life.

Common Questions

Will I feel high or out of control during my ketamine teatment?

No. You may feel dissociated (separated from normal thought patterns), but you’ll be conscious and safe throughout.

Ketamine doesn’t suppress symptoms—it rewires brain circuits. It also doesn’t have the dependency risks of benzodiazepines.

No. We support continuity of care and often work alongside your existing provider.

Ready to Move Forward?

Tell us your story. We’ll map the path forward.

We’ll listen, understand your needs, and see if ketamine therapy is the right fit. No pressure. No obligations. Just support, guidance, and clear answers.

Contact Us: 954-870-4768