Ketamine for OCD Treatment in Fort Lauderdale, FL

Real Hope For Those Who Feel Stuck In The Cycle

Dr. Carolyn Rodriguez discusses the promise of ketamine as a rapid acting treatment for anxiety disorders.

What is Ketamine Therapy?

Ketamine therapy is an innovative treatment approach that targets the glutamate system in the brain to interrupt the repetitive neural loops driving OCD. Unlike traditional SSRIs that can take weeks to show effects, ketamine works rapidly to reduce the intensity of intrusive thoughts and compulsive behaviors.

Originally used as an anesthetic, ketamine has emerged as a breakthrough treatment for treatment-resistant OCD. By blocking NMDA receptors and promoting neuroplasticity, it helps create new neural pathways that allow you to break free from obsessive-compulsive patterns that have controlled your life.

ketamine for mental health treatment image of brain

How Does Ketamine for OCD Work?

Ketamine targets the root cause of OCD at the neurological level. OCD is driven by dysregulated glutamate signaling, which creates rigid, repetitive thought patterns and behaviors. Ketamine modulates this system by:

Interrupting Neural Loops: Ketamine disrupts the overactive circuits between the orbitofrontal cortex, striatum, and thalamus—the brain regions responsible for obsessive thoughts and compulsive rituals.

Promoting Brain Plasticity: By increasing BDNF (Brain-Derived Neurotrophic Factor), ketamine helps your brain form new, healthier neural connections, making it easier to resist compulsions.

Reducing Hyperarousal: Ketamine calms the heightened anxiety that fuels the need to perform rituals, giving you space to challenge OCD patterns.

Rapid Symptom Relief: Many patients report significant reduction in intrusive thoughts and compulsive urges within hours to days, rather than the weeks or months required by traditional medications.

Do Any of These OCD Symptoms Feel Familiar?

You're stuck in checking loops you can't escape

Intrusive thoughts won't leave you alone

Rituals steal hours from your day

Contamination fears control where you go

Everything must feel "just right" or you panic

You've tried treatment but nothing has worked

OCD affects focus, sleep, relationships, and even physical health. It’s not just “in your head.” It’s a nervous system imbalance—and ketamine can help reset it.

What Are The Benefits of Ketamine for OCD?

man-happy-after-ketamine-for-ocd-treatment

Ketamine doesn’t just mask symptoms—it addresses OCD at its root by rewiring the neural circuits that trap you in obsessive-compulsive loops.

Unlike SSRIs that only manage surface-level symptoms, ketamine modulates the glutamate system, helping interrupt the overactive circuits between your orbitofrontal cortex, striatum, and thalamus—the regions responsible for intrusive thoughts and compulsive rituals—while enabling the formation of new, healthier neural pathways.

This fundamental shift is what makes the benefits so profound and long-lasting.

In a 2013 randomized controlled trial, 50% of patients with treatment-resistant OCD who received ketamine met criteria for treatment response (≥35% symptom reduction) one week after a single infusion, compared to 0% of those receiving placebo (Rodriguez et al., Neuropsychopharmacology).

man-happy-after-ketamine-for-ocd-treatment

Rapid Relief

Many patients notice meaningful improvement within 1-3 infusion sessions—often within 24-72 hours of their first treatment. This rapid response can be life-changing for those who have waited months or years for traditional OCD medications to work.

Breaks the Compulsion Cycle

Ketamine creates psychological space between intrusive thoughts and compulsive urges. Instead of automatically performing rituals, you gain the ability to pause and resist compulsions—breaking the patterns that have controlled your life.

Restores Mental Clarity

The mental exhaustion, brain fog, and decision fatigue that accompany chronic OCD often lift dramatically. Patients report clearer thinking and the ability to engage fully in work and relationships again, without constant mental rituals draining their energy.

Supports Better Sleep

By helping your nervous system down-regulate and reducing nighttime intrusive thoughts, ketamine often restores healthy sleep patterns. Many patients report falling asleep easier, staying asleep through the night, and waking refreshed instead of immediately anxious about rituals.

Why Choose One Mind for Your Ketamine Treatment?

We treat OCD seriously. And we do it safely.

physician oversight
Physician-guided:

Every treatment is overseen by a board-certified anesthesiologist

tailored protocols
Tailored protocols

We adjust dosing to your unique needs

gold-standard
Gold-standard care

6 infusions over 2–3 weeks (research-backed protocol)

collaborative care
Collaborative model

We can coordinate with your therapist or psychiatrist

“Patients come in spinning out. They leave feeling like they can breathe again.”

Looking for ketamine for depression, anxiety, PTSD, or chronic pain management in South Florida? Visit One Mind Wellness and Ketamine in Fort Lauderdale.

What to Expect During Your Ketamine Treatment

Infusion Time

45 minutes

Clinic Time

60 - 90 minutes total

Environment

Calm, private setting with medical supervisor

Experience

Often described as peaceful, floating, or emotionally releasing

Post-session

Some feel calm immediately, others feel better over 24–72 hours

integration support near me

Integration Support

We offer optional check-ins, guided reflections, or provider coordination after your infusions—so the breakthroughs you experience in-session carry into everyday life.

Common Questions

Will ketamine make my intrusive thoughts worse?

No. Ketamine actually reduces the intensity and frequency of intrusive thoughts by modulating the glutamate system. While you may feel dissociated during treatment, this creates therapeutic distance from obsessive patterns rather than amplifying them.

SSRIs work on serotonin and can take 8-12 weeks to show effects for OCD, with only 40-60% of patients responding. Ketamine targets the glutamate system and works within hours to days, offering hope for treatment-resistant OCD when SSRIs have failed.

No. Ketamine actually enhances the effectiveness of exposure and response prevention (ERP) therapy by reducing the anxiety that makes exposures difficult. Most patients continue their current medications and therapy while adding ketamine treatment.

Transparent Healing

Real People, Real Results

Great people who care. I’m not a Dr, but I would recommend a loved one try this route prior to being prescribed to lifelong medications with a laundry list of side effects. Thank you again team.
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g m.
8/30/2026
Super staff! The treatment was stellar. One Mund was a light in a very dark place for me. I am forever grateful.
READ MORE
Jay S.
8/10/2026
Best money I’ve ever spent. Ketamine therapy helped quiet my racing thoughts and gave me a sense of peace I hadn’t felt in a long time. I’m sleeping better, getting out of bed with more energy, and I finally feel like I have my motivation back to focus on building my business. The entire team is incredibly kind, compassionate, and professional. They made me feel comfortable and, most importantly, safe throughout every session. I’m truly grateful for this experience and highly recommend this clinic to anyone looking for real support on their healing journey.
READ MORE
Racquel J.
7/14/2026
I had an exceptional experience at One Mind Wellness and cannot recommend them highly enough. I was very nervous heading into my first session as I’m working through a lot of grief but from the moment I arrived I felt genuinely supported and cared for. Mike the concierge was incredibly kind and attentive and made sure I felt fully prepared and comfortable throughout the process. Dr. Topfer was extremely hands-on compassionate and thoughtful creating such a safe and reassuring environment. Even after my first session I noticed a sense of relief which has given me so much hope for the journey ahead. The entire team goes above and beyond to make the experience feel supportive professional and truly patient centered and I’m very grateful to have found them.
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Alexa D.
3/17/2026
I had an exceptional experience at One Mind Wellness, and I cannot recommend them highly enough.From the moment you walk in, you feel supported and cared for. Mike, the concierge, is wonderful — incredibly attentive, kind, and helpful throughout the entire process. He truly makes you feel comfortable and welcomed.Dr. Topfer and Dr. Greca are a top-notch team. Their professionalism, knowledge, and compassion made me feel that I was in the best possible hands. My neuropsychiatrist actually recommended ketamine therapy to me, which is what led me to One Mind Wellness, and I’m so grateful that I followed that advice.I completed six ketamine sessions, and the results have been life-changing. Before treatment, I struggled with rumination — my thoughts often felt stuck in a negative loop that I couldn’t break. Since completing the sessions, that pattern has lifted. I feel calmer, much less reactive, and more at peace mentally.I’ve also noticed improvements in my energy and my ability to focus. It truly feels like my mind has reset in a healthy way.My only regret is that I didn’t do this sooner.If you are considering ketamine therapy, you will be in excellent hands at One Mind Wellness.
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Kellie S.
3/08/2026
Dr. Graca and team are really top notch. I run a large healthcare company and know the industry well and these guys really go the extra mile. Ketamine saved me and I was so worried when moving from NYC, but Graca talked to all my other doctors and took great care of me
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Connor W.
12/24/2025
Great people who care. I’m not a Dr, but I would recommend a loved one try this route prior to being prescribed to lifelong medications with a laundry list of side effects. Thank you again team.
READ MORE
g m.
8/30/2026
Super staff! The treatment was stellar. One Mund was a light in a very dark place for me. I am forever grateful.
READ MORE
Jay S.
8/10/2026
Best money I’ve ever spent. Ketamine therapy helped quiet my racing thoughts and gave me a sense of peace I hadn’t felt in a long time. I’m sleeping better, getting out of bed with more energy, and I finally feel like I have my motivation back to focus on building my business. The entire team is incredibly kind, compassionate, and professional. They made me feel comfortable and, most importantly, safe throughout every session. I’m truly grateful for this experience and highly recommend this clinic to anyone looking for real support on their healing journey.
READ MORE
Racquel J.
7/14/2026

Start Your Journey To Calm And Clarity Today

Let’s begin with a private consultation that’s calm, caring, and completely focused on you. We’ll take things one step at a time, starting with a conversation designed to help you thrive. Our team will listen carefully, understand your unique needs, and determine if ketamine therapy is the right fit before moving forward. There’s no pressure or obligations—just compassionate support, expert guidance, and clear answers to all your questions. Fill out the form and we’ll reach out to provide the thoughtful care you deserve. Your story stays with us, always private and always respected.

Ready to Move Forward?

Tell us your story. We’ll map the path forward.

We’ll listen, understand your needs, and see if ketamine therapy is the right fit. No pressure. No obligations. Just support, guidance, and clear answers.

Contact Us: 954-870-4768