Break Free from Chronic Pain, Fatigue, and Fibro Fog
F. Perry Wilson, MD: How ketamine helps treat chronic pain
For individuals with fibromyalgia who have found little success with conventional treatment methods, ketamine infusion therapy represents an emerging therapeutic option worth considering.
This pharmaceutical agent, initially developed for anesthetic purposes, operates through mechanisms distinct from typical analgesic medications—specifically by modulating neural pain transmission pathways to deliver sustained symptom reduction.
When delivered via controlled intravenous protocols within our supervised clinical setting, this treatment approach aims to disrupt the persistent pain patterns characteristic of fibromyalgia and support improved daily functioning.
Fibromyalgia is characterized by central sensitization—a condition where the central nervous system amplifies pain signals and processes normal sensations as painful. Ketamine addresses this through multiple pathways:
NMDA Receptor Modulation: Blocks overactive pain receptors in the brain and spinal cord, reducing central sensitization and pain amplification.
Neuroinflammation Reduction: Decreases inflammatory processes in the central nervous system that contribute to widespread pain and fatigue.
Neurotransmitter Balance: Helps restore normal levels of serotonin, norepinephrine, and other key neurotransmitters involved in pain and mood regulation.
Brain Plasticity Enhancement: Promotes the formation of new neural connections, potentially reversing pain memory patterns established by chronic fibromyalgia.
Mood and Energy Support: Often provides rapid improvement in depression, anxiety, and energy levels commonly associated with fibromyalgia.
This comprehensive neurological approach makes ketamine uniquely effective for the multi-faceted nature of fibromyalgia symptoms.
Persistent aching, burning, or stabbing pain throughout your body, often in multiple locations
Specific areas of your body are extremely sensitive to pressure or touch
Profound exhaustion that doesn't improve with rest and interferes with daily activities
Difficulty concentrating, memory problems, and mental confusion that affects work and daily life
Trouble falling or staying asleep, non-restorative sleep, waking feeling unrefreshed
Significant joint and muscle stiffness, especially upon waking or after periods of inactivity
Fibromyalgia is a real physical condition affecting your nervous system and pain processing—and with the right approach, symptoms can be managed.
Ketamine doesn’t just mask pain—it addresses chronic pain at its source by rewiring how your nervous system processes and maintains pain signals.
Unlike opioids or NSAIDs that only provide temporary symptom relief, ketamine modulates NMDA receptors, helping calm overactive pain pathways in your nervous system while enabling the formation of healthier pain processing patterns.
This fundamental shift is what makes the benefits so profound and long-lasting.
IV ketamine infusions have shown >50% pain reduction in treatment-resistant fibromyalgia patients when administered at higher doses with regular maintenance treatments (Affaitati et al., 2023; Maheshwari et al., 2023).
Noticeable reduction in debilitating fatigue, allowing return to activities you enjoy
Reduced stiffness and pain allowing greater physical activity and independence
Relief from fibro fog with improved concentration, memory, and cognitive function
Deeper, more restorative sleep that helps break the pain-fatigue cycle
Pain management shouldn't feel like a dead end. At One Mind, we offer:
Board-certified physicians with extensive experience treating fibromyalgia and complex pain conditions.
Customized protocols based on your unique symptom profile, medical history, and treatment goals.
Private treatment rooms with continuous medical monitoring and supportive staff who understand fibromyalgia.
We coordinate with your PCP, therapist, or pain management team to prvide the best care possible.
“We help patients who were told there was nothing left to try. And we see them come back to life.”
About 2 hours (longer than mood infusions to support sustained pain relief)
2.5 – 3 hours total, including prep and recovery
Calm, private setting with medical supervisor
Some patients notice meaningful pain reduction within 1–3 sessions, while others experience gradual improvements over a full treatment series. Relief may include reduced pain intensity, improved mobility, or greater ability to engage in daily activities.
We provide follow-up boosters (if needed), integration coaching, and seamless communication with your existing providers to ensure continuity of care.
You may feel a sense of disconnection or stillness—but you’ll be safe, conscious, and medically monitored throughout.
Some patients experience several weeks to months of relief. Boosters are available based on need.
Real People, Real Results
Let’s begin with a private consultation that’s calm, caring, and completely focused on you. We’ll take things one step at a time, starting with a conversation designed to help you thrive. Our team will listen carefully, understand your unique needs, and determine if ketamine therapy is the right fit before moving forward. There’s no pressure or obligations—just compassionate support, expert guidance, and clear answers to all your questions. Fill out the form and we’ll reach out to provide the thoughtful care you deserve. Your story stays with us, always private and always respected.
Tell us your story. We’ll map the path forward.
We’ll listen, understand your needs, and see if ketamine therapy is the right fit. No pressure. No obligations. Just support, guidance, and clear answers.
Contact Us: 954-870-4768
